Georgetown College, Georgetown, Kentucky - Bachelors of Science in Biological Sciences Minor in Chemistry, 2007-2011
University of Kentucky, Lexington, Kentucky - Department of Pharmacology and Nutritional Sciences, 2012-Present
Many research groups speculate that activation of brown adipose tissue could be an endogenous means to maintaining metabolic health in states of overnutrition and obesity. Unfortunately, some groups have shown that obesity is associated with reduced energy expenditure in brown adipose tissue, yet mechanisms for this reduced activation have not been determined. Our preliminary data suggests that despite high-fat diet, CD47 deficiency preserves the classic multilocular phenotype of BAT, significantly increases UCP1 mRNA levels, and elevates core body temperature. This causes us to question whether CD47 has a novel role in regulating brown adipose tissue activation. My current research project is exploring a novel mechanism for brown adipose tissue dysfunction in obesity.